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Atypical Sarcoidosis Diagnosed by Massive Splenomegaly

Authors :
Satomi Saito
Shunichi Ariizumi
Yuki Yamanashi
Masakazu Yamamoto
Makiko Taniai
Katsutoshi Tokushige
Tomomi Kogiso
Kazuhisa Kodama
Source :
Internal Medicine
Publication Year :
2019
Publisher :
The Japanese Society of Internal Medicine, 2019.

Abstract

We examined a 22-year-old woman who was admitted to our hospital with abdominal distention. At 19 years of age, the patient presented with hepatosplenomegaly. She was examined several times in another hospital; however, the cause was unidentified. Our evaluation showed severe pancytopenia and a spleen 13×24 cm in size. The serum levels of angiotensin-converting enzyme and lysozyme were elevated. She was diagnosed with liver sarcoidosis based on non-caseating epithelioid granuloma in liver biopsy tissue. To improve the symptoms, splenectomy was performed, and her pancytopenia and symptoms improved. Sarcoidosis should be considered in cases of massive splenomegaly.

Details

Language :
English
ISSN :
13497235 and 09182918
Volume :
59
Issue :
5
Database :
OpenAIRE
Journal :
Internal Medicine
Accession number :
edsair.doi.dedup.....601d15ddb4db490afc379721ebcef976