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Atypical Sarcoidosis Diagnosed by Massive Splenomegaly
- Source :
- Internal Medicine
- Publication Year :
- 2019
- Publisher :
- The Japanese Society of Internal Medicine, 2019.
-
Abstract
- We examined a 22-year-old woman who was admitted to our hospital with abdominal distention. At 19 years of age, the patient presented with hepatosplenomegaly. She was examined several times in another hospital; however, the cause was unidentified. Our evaluation showed severe pancytopenia and a spleen 13×24 cm in size. The serum levels of angiotensin-converting enzyme and lysozyme were elevated. She was diagnosed with liver sarcoidosis based on non-caseating epithelioid granuloma in liver biopsy tissue. To improve the symptoms, splenectomy was performed, and her pancytopenia and symptoms improved. Sarcoidosis should be considered in cases of massive splenomegaly.
- Subjects :
- Liver sarcoidosis
Pathology
medicine.medical_specialty
Sarcoidosis
Pancytopenia
medicine.medical_treatment
Biopsy
Splenectomy
Massive splenomegaly
Hepatosplenomegaly
liver sarcoidosis
Spleen
Case Report
030204 cardiovascular system & hematology
03 medical and health sciences
Young Adult
0302 clinical medicine
hemic and lymphatic diseases
Internal Medicine
medicine
Humans
Granuloma
medicine.diagnostic_test
business.industry
General Medicine
medicine.disease
and splenectomy
medicine.anatomical_structure
Liver biopsy
massive splenomegaly
Splenomegaly
030211 gastroenterology & hepatology
Female
Muramidase
medicine.symptom
business
Subjects
Details
- Language :
- English
- ISSN :
- 13497235 and 09182918
- Volume :
- 59
- Issue :
- 5
- Database :
- OpenAIRE
- Journal :
- Internal Medicine
- Accession number :
- edsair.doi.dedup.....601d15ddb4db490afc379721ebcef976