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Fertile male tortoiseshell cat with true chimerism 38,XY/38,XY
- Source :
- Reproduction in domestic animals = ZuchthygieneREFERENCES. 55(9)
- Publication Year :
- 2020
-
Abstract
- The tortoiseshell coat colour is characteristic to female cats, and its occurrence in tomcats is very rare and associated with chromosome abnormalities (additional copy of X chromosome). The aim of this study was identification of the genetic basis of a case of tortoiseshell colour in a fertile Maine coon tomcat. Cytogenetic and molecular genetic studies were carried out with painting molecular probes (WCPP) specific to the X and Y sex chromosomes as well as a DNA microsatellite panel for the parentage verification of cats. Cytogenetic analysis revealed only a single set of sex chromosomes typical for male - 38,XY. The results of the microsatellite polymorphism obtained from DNA showed three alleles in locus FCA201 and four alleles in loci FCA149 and FCA441 in different tissues (blood, hair roots and testicles). Based on these results, the case was diagnosed as a true chimerism 38,XY/38,XY. To the best of our knowledge, this is the first case of a 38,XY/38,XY chimera diagnosed in cats, confirmed by genetic analysis.
- Subjects :
- Male
X Chromosome
Locus (genetics)
Biology
Genetic analysis
Chimerism
03 medical and health sciences
Chimera (genetics)
0302 clinical medicine
Endocrinology
Y Chromosome
Testis
Animals
Allele
X chromosome
Alleles
Genetics
030219 obstetrics & reproductive medicine
Pigmentation
0402 animal and dairy science
Chromosome
04 agricultural and veterinary sciences
040201 dairy & animal science
Fertility
visual_art
Karyotyping
visual_art.visual_art_medium
Cats
Microsatellite
Animal Science and Zoology
Tortoiseshell
Biotechnology
Microsatellite Repeats
Subjects
Details
- ISSN :
- 14390531
- Volume :
- 55
- Issue :
- 9
- Database :
- OpenAIRE
- Journal :
- Reproduction in domestic animals = ZuchthygieneREFERENCES
- Accession number :
- edsair.doi.dedup.....602a7ade95067b003f448a290ff8993d