EBV-associated gastric carcinoma in high- and low-incidence areas for nasopharyngeal carcinoma

Authors :: Trine Boysen
Jeppe Friborg
M Mohammadi
Anne Vinkel Hansen
Stephen Hamilton-Dutoit
Mads Melbye
B Vainer
Jan Wohlfahrt
Source :: British Journal of Cancer, Boysen, T, Muhamaddi, M, Melbye, M, Hamilton-Dutoit, S J, Vainer, B, Hansen, AV, Wohlfahrt, J & Friborg, J 2009, ' EBV-associated gastric carcinoma in high and low incidence areas for nasopharyngeal carcinoma ' British Journal of Cancer, vol. 101, no. 3, pp. 530-3 ., Aarhus University
Publication Year :: 2009
Publisher :: Springer Science and Business Media LLC, 2009.
Abstract: Background: Approximately 10% of gastric carcinomas are associated with Epstein–Barr virus (EBV). The Inuit in Greenland have a high incidence of EBV-associated nasopharyngeal carcinoma. Methods: We conducted a population-based case–control study comparing gastric carcinomas in Greenland and in Denmark. Results: The prevalence rate of EBV-associated gastric carcinomas was 8.5% in both populations. Conclusion: The findings of this study argue against a general susceptibility to EBV-associated carcinomas among the Inuit.

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