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Antifungal and Antiparasitic Drug Delivery
- Source :
- E-Prints Complutense. Archivo Institucional de la UCM, instname, Pharmaceutics, Pharmaceutics, Vol 12, Iss 324, p 324 (2020)
- Publication Year :
- 2020
- Publisher :
- MDPI, 2020.
-
Abstract
- Fungal and parasitic diseases affect more than a billion people across the globe, one-sixth of the world’s population, mostly located in developing countries. The lack of effective and safer treatments combined with a deficient diagnosis lead to serious chronic illness or even death. There is a mismatch between the rate of drug resistance and the development of new medicines. Formulation of antifungal and antiparasitic drugs adapted to different administration routes is challenging, bearing in mind their poor water solubility, which limits their bioavailability and efficacy. Hence, there is an unmet clinical need to develop vaccines and novel formulations and drug delivery strategies that can improve the bioavailability and therapeutic effect by enhancing their dissolution, increasing their chemical potency, stabilising the drug and targeting high concentration of drug to the infection sites. This Editorial regards the ten research contributions presented in the Special Issue “Antifungal and Antiparasitic Drug Delivery”.
- Subjects :
- liposomes
Drug
trypanosomiasis
medicine.medical_specialty
quality by design
Antiparasitic
medicine.drug_class
azoles
media_common.quotation_subject
Farmacología
Tecnología de los alimentos
Population
malaria
lcsh:RS1-441
Pharmaceutical Science
Drug resistance
emulsions
lcsh:Pharmacy and materia medica
combined therapy
Amphotericin B
Medicine
Potency
aspergillosis
Intensive care medicine
education
leishmaniasis
media_common
education.field_of_study
business.industry
candidiasis
amphotericin B
Bioavailability
Editorial
transferosomes
Drug delivery
nanoparticles
business
medicine.drug
Subjects
Details
- Database :
- OpenAIRE
- Journal :
- E-Prints Complutense. Archivo Institucional de la UCM, instname, Pharmaceutics, Pharmaceutics, Vol 12, Iss 324, p 324 (2020)
- Accession number :
- edsair.doi.dedup.....615d954cbc1c759b7d2809dfee07113c