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Novel polyketide from Fusarium verticillioide G102 as NPC1L1 inhibitors
- Source :
- Natural Product Research. :1-7
- Publication Year :
- 2023
- Publisher :
- Informa UK Limited, 2023.
-
Abstract
- One novel polyketide, fusaritide A (1), was isolated from a marine fish-derived halotolerant fungal strain Fusarium verticillioide G102. The structure was determined through extensive spectroscopic analysis and high-resolution electrospray ionization mass spectrometry. Fusaritide A (1) with unprecedented structure reduced cholesterol uptake by inhibiting Niemann-Pick C1-Like 1 (NPC1L1).
- Subjects :
- Organic Chemistry
Plant Science
Biochemistry
Analytical Chemistry
Subjects
Details
- ISSN :
- 14786427 and 14786419
- Database :
- OpenAIRE
- Journal :
- Natural Product Research
- Accession number :
- edsair.doi.dedup.....616b13bcf1f7c0c1799c1e6d864a736d