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Medical and surgical management of primary cardiac tumours in infants and children
- Publication Year :
- 2013
-
Abstract
- Primary cardiac tumours in infants and children are extremely rare, with an estimated incidence of 0.2% according to echocardiographic studies. Owing to their rarity, there is very little literature available, and most knowledge is based on collections of case reports. Therefore, we reviewed retrospectively our 27 years of clinical experience on the overall management of cardiac tumours among children in order to improve not only our knowledge but also to provide others with information about the incidence, clinical presentation, management, and long-term outcome of this rare disease. Between April, 1982 and April, 2009, 52 children were diagnosed with cardiac tumours at our Institution. Medical records and follow-up echocardiographic evaluations were studied. The diagnosis was prenatal in 35% of the patients. The most frequent tumour types were rhabdomyomas (61.5%), fibromas (15.4%), and myxomas (5.8%). There were no cases of primary malignant tumours. All diagnoses were achieved using two-dimensional echocardiography, and for 12 patients a pathological analysis was carried out. A total of 41 patients (79%) were managed medically, whereas 11 (21%) patients underwent surgical treatment. At a mean follow-up of 7.2 ± 5.4 years, two patients died of complications related to cardiac transplantation; all the remaining patients are in excellent clinical condition. In conclusion, cardiac tumours in paediatric practice are usually clinically and histologically benign. Only a few cases need surgery. Up to one-third of the cardiac masses are detectable prenatally. Rhabdomyoma is the most common histotype, followed by fibroma and myxoma. The long-term prognosis is generally good.
- Subjects :
- Male
Pediatrics
medicine.medical_specialty
Adolescent
Fibroma
Rhabdomyoma
Ultrasonography, Prenatal
Cohort Studies
Heart Neoplasms
Neoplasms, Multiple Primary
Pregnancy
medicine
Humans
Child
Retrospective Studies
business.industry
Incidence (epidemiology)
Medical record
Infant, Newborn
Teratoma
Myxoma
Infant
Retrospective cohort study
Arrhythmias, Cardiac
General Medicine
medicine.disease
Surgery
Transplantation
Echocardiography
Neoplasm Regression, Spontaneous
Child, Preschool
Pediatrics, Perinatology and Child Health
Asymptomatic Diseases
Heart Transplantation
Female
Cardiology and Cardiovascular Medicine
business
Rare disease
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Accession number :
- edsair.doi.dedup.....626ac3849b4ae4d8cae2067373154b93