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Ultrasound Computer-Aided Diagnosis (CAD) Based on the Thyroid Imaging Reporting and Data System (TI-RADS) to Distinguish Benign from Malignant Thyroid Nodules and the Diagnostic Performance of Radiologists with Different Diagnostic Experience
- Source :
- Medical Science Monitor : International Medical Journal of Experimental and Clinical Research
- Publication Year :
- 2020
- Publisher :
- International Scientific Information, Inc., 2020.
-
Abstract
- strongBACKGROUND/strongThe diagnosis of thyroid cancer and distinguishing benign from malignant thyroid nodules by junior radiologists can be challenging. This study aimed to develop a computer-aided diagnosis (CAD) system based on the Thyroid Imaging Reporting and Data System (TI-RADS) to distinguish benign from malignant thyroid nodules by analyzing ultrasound images to improve the diagnostic performance of junior radiologists.strongMATERIAL AND METHODS/strongA modified TI-RADS based on a convolutional neural network (CNN) was used to develop the CAD system. This retrospective study reviewed 789 thyroid nodules from 695 patients and included radiologists with different diagnostic experience. Five study groups included the CAD group, the junior radiologist group, the intermediate-level radiologist group, the senior radiologist group, and the group in which the junior radiologist used the CAD system. The ultrasound findings were reviewed and compared with the histopathology diagnosis.strongRESULTS/strongThe CAD system for the diagnosis of thyroid cancer showed an accuracy of 80.35%, a sensitivity of 80.64%, a specificity of 80.13%, a positive predictive value (PPV) of 76.02%, a negative predictive value (NPV) of 84.12%, and an area under the receiver operating characteristic (ROC) curve (AUC) of 0.87. The accuracy of the junior radiologists in diagnosing thyroid cancer using CAD was similar to that of intermediate-level radiologists (79.21%ivs/i. 77.57%; P=0.427).strongCONCLUSIONS/strongThe use of ultrasound CAD based on the TI-RADS showed potential for distinguishing between benign and malignant thyroid nodules and improved the diagnostic performance of junior radiologists.
- Subjects :
- Adult
Male
Thyroid nodules
medicine.medical_specialty
education
Thyroid Gland
CAD
030204 cardiovascular system & hematology
Sensitivity and Specificity
Diagnosis, Differential
03 medical and health sciences
0302 clinical medicine
Clinical Research
Diagnosis
Radiologists
Image Processing, Computer-Assisted
medicine
Humans
Thyroid Neoplasms
Diagnosis, Computer-Assisted
Thyroid Nodule
Thyroid cancer
Ultrasonography
Receiver operating characteristic
business.industry
Thyroid
Ultrasound
Retrospective cohort study
General Medicine
Middle Aged
medicine.disease
body regions
medicine.anatomical_structure
ROC Curve
Computer-aided diagnosis
Area Under Curve
030220 oncology & carcinogenesis
Female
Radiology
business
Subjects
Details
- ISSN :
- 16433750
- Volume :
- 26
- Database :
- OpenAIRE
- Journal :
- Medical Science Monitor
- Accession number :
- edsair.doi.dedup.....629e6861d5f862a034424508f8f018dc