Back to Search Start Over

Anesthesia: Synaptic power failure

Authors :
Bruno van Swinderen
Max B. Kelz
Source :
Current Biology. 32:R781-R783
Publication Year :
2022
Publisher :
Elsevier BV, 2022.

Abstract

One of the greatest unresolved mysteries in medicine relates to the molecular and neuronal mechanisms through which general anesthetics abolish perception. A new study in mice with mutations affecting mitochondrial complex 1 suggests that anesthetic-disruption of cellular energetics impairs endocytosis to alter synaptic function.

Subjects

Subjects :
Neurons
Mice
Anesthetics, General
Animals
Anesthesia
General Agricultural and Biological Sciences
General Biochemistry, Genetics and Molecular Biology

Details

ISSN :
09609822
Volume :
32
Database :
OpenAIRE
Journal :
Current Biology
Accession number :
edsair.doi.dedup.....62adb4475f708aa2370080a4746c03e1
Full Text :
https://doi.org/10.1016/j.cub.2022.06.043
Full Text Access
View/download PDF

Tools

Authors Abstract Subjects Details