Back to Search
Start Over
A 2-year follow-up survey of 523 cases with peripheral nerve injuries caused by the earthquake in Wenchuan, China
- Source :
- Neural Regeneration Research, Neural Regeneration Research, Vol 10, Iss 2, Pp 252-259 (2015)
- Publication Year :
- 2015
- Publisher :
- Medknow, 2015.
-
Abstract
- We performed a 2-year follow-up survey of 523 patients with peripheral nerve injuries caused by the earthquake in Wenchuan, Sichuan Province, China. Nerve injuries were classified into three types: type I injuries were nerve transection injuries, type II injuries were nerve compression injuries, and type III injuries displayed no direct neurological dysfunction due to trauma. In this study, 31 patients had type I injuries involving 41 nerves, 419 had type II injuries involving 823 nerves, and 73 had type III injuries involving 150 nerves. Twenty-two patients had open transection nerve injury. The restoration of peripheral nerve function after different treatments was evaluated. Surgical decompression favorably affected nerve recovery. Physiotherapy was effective for type I and type II nerve injuries, but not substantially for type III nerve injury. Pharmacotherapy had little effect on type II or type III nerve injuries. Targeted decompression surgery and physiotherapy contributed to the effective treatment of nerve transection and compression injuries. The Louisiana State University Health Sciences Center score for nerve injury severity declined with increasing duration of being trapped. In the first year after treatment, the Louisiana State University Health Sciences Center score for grades 3 to 5 nerve injury increased by 28.2% to 81.8%. If scores were still poor (0 or 1) after a 1-year period of treatment, further treatment was not effective.
- Subjects :
- calcium-sensing receptor
neurons
Poison control
NPS 2143
lcsh:RC346-429
Occupational safety and health
electrophysiological function
compartment syndrome
NSFC grants
axon growth
Medicine
calcilytic
Schwann cells
CD133
contusion
nerve regeneration
edaravone
motor function
α7-nicotinic acetylcholine receptor
nerve decompression
surgical decompression
fluorescent quantitative PCR
glial fibrillary acidic protein
immunohistochemistry
Peripheral nerve injury
neuroprotection
surgery therapy
medicine.symptom
neural regeneration
MRI
Research Article
medicine.medical_specialty
mice
Notch
brain
amyloid-β
tumor necrosis factor α
neurological function
Pharmacotherapy
Developmental Neuroscience
Peripheral nerve
electroacupuncture
Injury prevention
nestin
blood circulation
peripheral nerve injury
cell transplantation
astrocytoma
LSUHSC score
lcsh:Neurology. Diseases of the nervous system
physiotherapy
cell apoptosis
business.industry
astrocytes
spinal cord
Nerve injury
spinal cord injury
Surgery
Alzheimer′s disease
inflammation
earthquake
nitromemantine
Ca 2+
intervertebral disc
immunodeficiency (BALB/c) mice
Nogo-A
business
Biomedical sciences
Subjects
Details
- ISSN :
- 16735374
- Volume :
- 10
- Database :
- OpenAIRE
- Journal :
- Neural Regeneration Research
- Accession number :
- edsair.doi.dedup.....63389c1a44183c96ee7a9e453f1a6d2d