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Biomarkers of Acute Lung Lesion

Authors :
Ye. V. Grigoryev
Yu. A. Churlyaev
A. S. Razumov
Source :
Obŝaâ Reanimatologiâ, Vol 2, Iss 4, Pp 94-99 (2006)
Publication Year :
2006
Publisher :
Russian Academy of Medical Sciences, 2006.

Abstract

The paper analyzes the data available in the literature on the diagnostic value of biological markers of acute lung lesion (ALL) in critical conditions. The study of the diagnostic and prognostic values of biological markers of ALL is shown to be a promising line in the section of critical conditions. The biological markers of ALL will have the highest effectiveness in evaluating the development of ALL at the preclinical stage, in differentiating the exudative and proliferative stages of ALL/acute respiratory distress syndrome, and defining indications for respiratory support. The biological markers of ALL are capable to predict the development of ventilator-induced lung lesion. The analysis of gene expression and the study of an array of DNA nucleotide sequence in the cells are of the greatest diagnostic and prognostic value in determining the predisposition of cytokines and intercellular signal molecules to synthesis.

Details

Language :
Russian
ISSN :
24117110 and 18139779
Volume :
2
Issue :
4
Database :
OpenAIRE
Journal :
Obŝaâ Reanimatologiâ
Accession number :
edsair.doi.dedup.....635b647d5db2d79680ca05c8ee3ac35b