Supplementary Figures S1-S6 and Figure Legends from Cyclin-Dependent Kinase 5 Decreases in Gastric Cancer and Its Nuclear Accumulation Suppresses Gastric Tumorigenesis

Supplementary Figures S1-S6 and Figure Legends. Figure S1. Western blotting and RT-PCR results depicting CDK5 expression levels from 171 patients. Figure S2. Immunofluorescence staining of CDK1, CDK2, CDK3, and CDK4 in gastric cells. Figure S3. Nuclear/cytoplasmic distribution of CDK5 during cell cycle activity in gastric cancer cells. Figure S4. Flow Cytometry assay for identification of synchronized gastric cancer cells. Figure S5. Gastric cancer cells overexpressing nuclear CDK5 or CDK5-KD cells exhibited a much retarded in vitro growth rate than control cells. Figure S6. NS-0011 induced the nuclear translocation of CDK5 in MGC-803 cells by dose dependent.