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Characteristics of exercise intolerance in different subgroups of pulmonary arterial hypertension associated with congenital heart disease

Authors :
Hong-Da, Zhang
Yi, Yan
Yang-Yang, He
Qian-Qian, Liu
Fu-Hua, Peng
Xin-Xin, Yan
Zhi-Yan, Han
Source :
International Journal of Cardiology. 375:29-35
Publication Year :
2023
Publisher :
Elsevier BV, 2023.

Abstract

Exercise intolerance is a major manifestation of pulmonary arterial hypertension associated with congenital heart disease (PAH-CHD). We aimed to investigate the characteristics of exercise intolerance in different subgroups of PAH-CHD.We retrospectively enrolled 171 adult patients with PAH-CHD and 30 age and sex-matched healthy subjects and performed cardiopulmonary exercise testing. Gas exchange parameters, including peak oxygen uptake (peak V̇oThe median age of patients at enrollment was 27.8 years, and 131 (76.6%) were female. Peak V̇oExercise capacity was severely reduced in patients with PAH-CHD. Among the four subgroups, patients with Eisenmenger syndrome had the worst exercise capacity and ventilatory efficiency.

Details

ISSN :
01675273
Volume :
375
Database :
OpenAIRE
Journal :
International Journal of Cardiology
Accession number :
edsair.doi.dedup.....639cce4dd5495ccf83e796985ef07951