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Liquid Crystal Gel Reduces Age Spots by Promoting Skin Turnover

Authors :
Satomi Kato
Teruaki Nagasawa
Ariella Coler-Reilly
Mina Musashi
Yoko Yamaguchi
Yoshiki Kubota
Source :
Cosmetics, Vol 1, Iss 3, Pp 202-210 (2014), Cosmetics, Volume 1, Issue 3, Pages 202-210
Publication Year :
2014
Publisher :
MDPI AG, 2014.

Abstract

Studies have shown that liquid crystals structurally resembling the intercellular lipids in the stratum corneum can beneficially affect the skin when applied topically by stimulating the skin’s natural regenerative functions and accelerating epidermal turnover. In the present study, the effects of applying low concentrations of a liquid crystal gel of our own creation were evaluated using epidermal thickening in mouse skin as an assay for effective stimulation of epidermal turnover. A liquid crystal gel was also applied topically to human facial skin, and analysis was conducted using before-and-after photographs of age spots, measurements of L* values that reflect degree of skin pigmentation, single-layer samples of the stratum corneum obtained via tape-stripping, and measurements of trans-epidermal water loss that reflect the status of the skin’s barrier function. The results suggested that cost-effective creams containing as low as 5% liquid crystal gel might be effective and safely sold as skin care products targeting age spots and other problems relating to uneven skin pigmentation.

Details

ISSN :
20799284
Volume :
1
Database :
OpenAIRE
Journal :
Cosmetics
Accession number :
edsair.doi.dedup.....63dde9ef076a7d18003654913145ddd0
Full Text :
https://doi.org/10.3390/cosmetics1030202