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Liquid Crystal Gel Reduces Age Spots by Promoting Skin Turnover
- Source :
- Cosmetics, Vol 1, Iss 3, Pp 202-210 (2014), Cosmetics, Volume 1, Issue 3, Pages 202-210
- Publication Year :
- 2014
- Publisher :
- MDPI AG, 2014.
-
Abstract
- Studies have shown that liquid crystals structurally resembling the intercellular lipids in the stratum corneum can beneficially affect the skin when applied topically by stimulating the skin’s natural regenerative functions and accelerating epidermal turnover. In the present study, the effects of applying low concentrations of a liquid crystal gel of our own creation were evaluated using epidermal thickening in mouse skin as an assay for effective stimulation of epidermal turnover. A liquid crystal gel was also applied topically to human facial skin, and analysis was conducted using before-and-after photographs of age spots, measurements of L* values that reflect degree of skin pigmentation, single-layer samples of the stratum corneum obtained via tape-stripping, and measurements of trans-epidermal water loss that reflect the status of the skin’s barrier function. The results suggested that cost-effective creams containing as low as 5% liquid crystal gel might be effective and safely sold as skin care products targeting age spots and other problems relating to uneven skin pigmentation.
- Subjects :
- Aging
skin care
Pharmaceutical Science
Stimulation
Dermatology
lcsh:Chemistry
age spots
Liquid crystal
Stratum corneum
medicine
stratum corneum
Chemical Engineering (miscellaneous)
liquid crystal
Barrier function
Skin care
Chromatography
integumentary system
Spots
Chemistry
medicine.anatomical_structure
lcsh:QD1-999
intercellular lipids
Mouse skin
Surgery
skin turnover
Epidermal thickening
Subjects
Details
- ISSN :
- 20799284
- Volume :
- 1
- Database :
- OpenAIRE
- Journal :
- Cosmetics
- Accession number :
- edsair.doi.dedup.....63dde9ef076a7d18003654913145ddd0
- Full Text :
- https://doi.org/10.3390/cosmetics1030202