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DNP NMR spectroscopy reveals new structures, residues and interactions in wild spider silks

Authors :
Marc-Antoine Sani
Michael M. Kasumovic
James M. Hook
Aditya Rawal
Hamish C Craig
Sean J. Blamires
Source :
Chemical Communications. 55:4687-4690
Publication Year :
2019
Publisher :
Royal Society of Chemistry (RSC), 2019.

Abstract

DNP solid state NMR spectroscopy allows non-targeted analysis of wild spider silk in unprecedented detail at natural abundance, revealing hitherto unreported features across several species. A >50-fold signal enhancement for each silk, enables the detection of novel H-bonding networks and arginine conformations, and the post-translational modified amino acid, hydroxyproline.

Details

ISSN :
1364548X and 13597345
Volume :
55
Database :
OpenAIRE
Journal :
Chemical Communications
Accession number :
edsair.doi.dedup.....6418f10e2e3cb419d7a550c2353ecf4d
Full Text :
https://doi.org/10.1039/c9cc01045a