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Treating an oft-unrecognized and troublesome entity: using gastric electrical stimulation to reduce symptoms of malignancy-associated gastroparesis
- Source :
- Supportive Care in Cancer. 25:27-31
- Publication Year :
- 2016
- Publisher :
- Springer Science and Business Media LLC, 2016.
-
Abstract
- Malignancy-associated gastroparesis (MAG) is a cause of morbidity in cancer patients but therapies are lacking. Gastric electrical stimulation (GES) is a novel treatment for MAG. Here, we describe 19 patients with MAG who underwent temporary GES placement. Nineteen patients (6 males, 13 females) with various malignancies were reviewed for symptom scores and physiologic measures at baseline and after temporary GES placement. Symptoms were scored by three variables: nausea (N), vomiting (V), and GI total symptom score (TSS). Physiologic profiles were measured by solid and liquid phase gastric emptying scans (GET) at 1, 2, and 4 h and cutaneous electrogastrogram (EGG) and mucosal electrogram (EG) frequencies. Symptoms were measured for 5 days after temporary endoscopic GES placement, and measures were repeated post GES placement. Baseline GET results displayed delayed gastric emptying in 16 of 19 patients (mean solid retention 21.7 % at 4 h, normal
- Subjects :
- Adult
Male
medicine.medical_specialty
Gastroparesis
Nausea
Electric Stimulation Therapy
Malignancy
Gastroenterology
03 medical and health sciences
0302 clinical medicine
Electrogastrogram
Internal medicine
medicine
Humans
Prospective Studies
Prospective cohort study
Aged
Aged, 80 and over
medicine.diagnostic_test
Gastric emptying
business.industry
Cancer
Prostheses and Implants
Middle Aged
medicine.disease
Surgery
Oncology
030220 oncology & carcinogenesis
Vomiting
Female
030211 gastroenterology & hepatology
medicine.symptom
business
Subjects
Details
- ISSN :
- 14337339 and 09414355
- Volume :
- 25
- Database :
- OpenAIRE
- Journal :
- Supportive Care in Cancer
- Accession number :
- edsair.doi.dedup.....645f03306b4fd73b793e72a83f327bba