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Utility of magnetic resonance imaging in Crohn's associated sacroiliitis:A cross-sectional study
- Source :
- Malik, F, Scherl, E, Weber, U, Carrino, J A, Epsten, M, Wichuk, S, Pedersen, S J, Paschke, J, Schwartzman, S, Kroeber, G, Maksymowych, W P, Longman, R & Mandl, L A 2021, ' Utility of magnetic resonance imaging in Crohn's associated sacroiliitis : A cross-sectional study ', International Journal of Rheumatic Diseases, vol. 24, no. 4, pp. 582-590 . https://doi.org/10.1111/1756-185X.14081, Int J Rheum Dis
- Publication Year :
- 2021
-
Abstract
- OBJECTIVE: Prevalence of sacroiliitis in Crohn’s disease (CD) is variable depending on defining criteria. This study utilized standardized sacroiliac joint (SIJ) MRI to identify sacroiliitis in CD patients and its association with clinical and serological markers. METHODS: In this cross-sectional study, consecutive adult subjects with CD were prospectively enrolled from an inflammatory bowel disease clinic. All subjects underwent SIJ MRI. Data collected included CD duration, history of joint/back pain, HLA-B27 status, Bath Ankylosing Spondylitis Metrology Index (BASMI), Bath Ankylosing Spondylitis Disease Activity Index, Harvey-Bradshaw Index (HBI) for activity of CD, Ankylosing Spondylitis Disease Activity Score, C-reactive protein, and various serologic markers of inflammation. Three blinded readers reviewed MRIs for active and/or structural lesions according to the Spondyloarthritis Research Consortium of Canada modules. RESULTS: 33 CD patients were enrolled: 76% female, 80% white, median age 36.4 years (IQR 27.2–49.0), moderate CD activity (mean HBI 8.8±SD 4.5). 19 subjects (58%) reported any back pain, 13 of whom met ASAS inflammatory back pain criteria. 4 subjects (12%) showed sacroiliitis using global approach and 6 (18%) met ASAS imaging criteria of sacroiliitis. Older age (mean 51.2 ± SD 12.5 vs 37.2 ± 14; p=0.04), history of dactylitis (50.0% vs 3.4%, p=0.03) and worse BASMI (4.1 ± 0.7 vs 2.4 ± 0.8, p=
- Subjects :
- Adult
Male
medicine.medical_specialty
back pain
Article
sacroiliitis
Dactylitis
Young Adult
03 medical and health sciences
0302 clinical medicine
Crohn Disease
Rheumatology
Predictive Value of Tests
Interquartile range
Internal medicine
Prevalence
medicine
Back pain
Humans
magnetic resonance imaging
Serologic Tests
Prospective Studies
Sacroiliitis
030212 general & internal medicine
030203 arthritis & rheumatology
Sacroiliac joint
Ankylosing spondylitis
Crohn's disease
medicine.diagnostic_test
business.industry
Magnetic resonance imaging
Middle Aged
medicine.disease
Magnetic Resonance Imaging
cytokines
Cross-Sectional Studies
medicine.anatomical_structure
Cytokines
Female
New York City
Inflammation Mediators
medicine.symptom
business
Biomarkers
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Journal :
- Malik, F, Scherl, E, Weber, U, Carrino, J A, Epsten, M, Wichuk, S, Pedersen, S J, Paschke, J, Schwartzman, S, Kroeber, G, Maksymowych, W P, Longman, R & Mandl, L A 2021, ' Utility of magnetic resonance imaging in Crohn's associated sacroiliitis : A cross-sectional study ', International Journal of Rheumatic Diseases, vol. 24, no. 4, pp. 582-590 . https://doi.org/10.1111/1756-185X.14081, Int J Rheum Dis
- Accession number :
- edsair.doi.dedup.....6462ac706ff69bcafad24af63fe1ad71