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Assessing the Performance of Morphologic and Echogenic Features in Median Nerve Ultrasound for Carpal Tunnel Syndrome Diagnosis
- Source :
- Journal of Ultrasound in Medicine. 39:1165-1174
- Publication Year :
- 2019
- Publisher :
- Wiley, 2019.
-
Abstract
- To assess the feasibility of using ultrasound (US) image features related to the median nerve echogenicity and shape for carpal tunnel syndrome (CTS) diagnosis.In 31 participants (21 healthy participants and 10 patients with CTS), US images were collected with a 30-MHz transducer from median nerves at the wrist crease in 2 configurations: a neutral position and with wrist extension. Various morphologic features, including the cross-sectional area (CSA), were calculated to assess the nerve shape. Carpal tunnel syndrome commonly results in loss of visualization of the nerve fascicular pattern on US images. To assess this phenomenon, we developed a nerve-tissue contrast index (NTI) method. The NTI is a ratio of average brightness levels of surrounding tissue and the median nerve, both calculated on the basis of a US image. The area under the curve (AUC) from a receiver operating characteristic curve analysis and t test were used to assess the usefulness of the features for differentiation of patients with CTS from control participants.We obtained significant differences in the CSA and NTI parameters between the patients with CTS and control participants (P .01), with the corresponding highest AUC values equal to 0.885 and 0.938, respectively. For the remaining investigated morphologic features, the AUC values were less than 0.685, and the differences in means between the patients and control participants were not statistically significant (P .10). The wrist configuration had no impact on differences in average parameter values (P .09).Patients with CTS can be differentiated from healthy individuals on the basis of the median nerve CSA and echogenicity. Carpal tunnel syndrome is not manifested in a change of the median nerve shape that could be related to circularity or contour variability.
- Subjects :
- Adult
Male
Wrist Joint
Wrist
Sensitivity and Specificity
030218 nuclear medicine & medical imaging
Diagnosis, Differential
03 medical and health sciences
0302 clinical medicine
medicine
Humans
Radiology, Nuclear Medicine and imaging
Carpal tunnel syndrome
Aged
Ultrasonography
Fascicular Pattern
030219 obstetrics & reproductive medicine
Radiological and Ultrasound Technology
Receiver operating characteristic
business.industry
Ultrasound
Area under the curve
Reproducibility of Results
Echogenicity
medicine.disease
Carpal Tunnel Syndrome
Median nerve
Median Nerve
nervous system diseases
medicine.anatomical_structure
Feasibility Studies
Female
Nuclear medicine
business
Subjects
Details
- ISSN :
- 15509613 and 02784297
- Volume :
- 39
- Database :
- OpenAIRE
- Journal :
- Journal of Ultrasound in Medicine
- Accession number :
- edsair.doi.dedup.....649fee1d228790e6d0947a35d5ff3343