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The seroprevalence of the hepatitis B virus in Italian medical students after 3 decades since the introduction of universal vaccination
- Source :
- International Journal of Occupational Medicine and Environmental Health. 35:75-80
- Publication Year :
- 2022
- Publisher :
- Nofer Institute of Occupational Medicine, 2022.
-
Abstract
- OBJECTIVES Since 1991 hepatitis B vaccination has been mandatory for all newborns in Italy. The aim of the study was to verify the long-term seroprevalence and the efficacy of hepatitis B vaccination in medical students of the University of Siena. MATERIAL AND METHODS A cross-sectional observational study was conducted on a population of 850 medical students of the University of Siena (322 males and 528 females, mean age: 23 years) by obtaining from the medical reports the serological analysis data for the total anti-hepatitis B antibodies (HBsAb) and information on hepatitis B vaccination (number of vaccine doses, age at the first vaccination, time since the final vaccination dose, country of origin). Raw odds ratios (ORs) and 95% confidence intervals (CIs) were initially calculated to evaluate the association between 2 variables. The adjusted ORs were then calculated using a multivariate logistic regression model to study the association between the variables and the possible confounding factors. RESULTS Overall, 593 students (69.76%) were immunized against hepatitis B, while 257 (30.24%) had HBsAb antibody titer
- Subjects :
- Adult
Male
Hepatitis B virus
Students, Medical
Population
medicine.disease_cause
Young Adult
Seroepidemiologic Studies
Medical
medicine
Humans
Seroprevalence
Hepatitis B Vaccines
Students
education
Hepatitis B
Hepatitis B antibodies
Immunization
Medical students
Seroepidemiological studies
Vaccination
Cross-Sectional Studies
Female
Hepatitis B Antibodies
Hepatitis B Surface Antigens
Infant, Newborn
Italy
education.field_of_study
business.industry
Public Health, Environmental and Occupational Health
Infant
General Medicine
Odds ratio
Newborn
medicine.disease
Confidence interval
business
Demography
Subjects
Details
- ISSN :
- 1896494X and 12321087
- Volume :
- 35
- Database :
- OpenAIRE
- Journal :
- International Journal of Occupational Medicine and Environmental Health
- Accession number :
- edsair.doi.dedup.....64debd81beb4b64651a8d7926d01603c