Supplementary Methods and Supplementary Figures 1 through 7 from Assessment of the In Vivo Activity of PI3K and MEK Inhibitors in Genetically Defined Models of Colorectal Cancer

This file contains supplementary methods and figures describing tumour severity scoring and tumour area measurements in all three tumour model. Additionally, histological representation of cleaved caspase 3 and BrdU staining and western blots showing activation of MAPK and PI3K signalling pathways in tumour models.