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Critical review on proteotypic peptide marker tracing for six allergenic ingredients in incurred foods by mass spectrometry
- Source :
- Food Research International, Food Research International, Elsevier, 2020, 128, pp.108747. ⟨10.1016/j.foodres.2019.108747⟩, Food research international (2020). doi:10.1016/j.foodres.2019.108747, info:cnr-pdr/source/autori:Rosa Pilolli1, Chiara Nitride2, Nathalie Gillard3, Anne-Catherine Huet3, Christof van Poucke4, Marc de Loose4, Olivier Tranquet5, Collette Larré5, Karine Adel-Patient6, Hervé Bernard6, E. N. Clare Mills2, and Linda Monaci1*/titolo:CRITICAL REVIEW ON PROTEOTYPIC PEPTIDE MARKERS TRACING FOR SIX ALLERGENIC INGREDIENTS IN INCURRED FOODS BY MASS SPECTROMETRY/doi:10.1016%2Fj.foodres.2019.108747/rivista:Food research international/anno:2020/pagina_da:/pagina_a:/intervallo_pagine:/volume, Pilolli, R, Nitride, C, Gillard, N, Huet, A-C, van Poucke, C, de Loose, M, Tranquet, O, Larré, C, Adel-Patient, K, Bernard, H, Mills, E N C & Monaci, L 2020, ' Critical review on proteotypic peptide marker tracing for six allergenic ingredients in incurred foods by mass spectrometry ', Food Research International, vol. 128, pp. 108747 . https://doi.org/10.1016/j.foodres.2019.108747, Food Research International, 2020, 128, pp.108747. ⟨10.1016/j.foodres.2019.108747⟩
- Publication Year :
- 2020
- Publisher :
- HAL CCSD, 2020.
-
Abstract
- Peptide marker identification is one of the most important steps in the development of a mass spectrometry (MS) based method for allergen detection, since the robustness and sensitivity of the overall analytical method will strictly depend on the reliability of the proteotypic peptides tracing for each allergen. The European legislation in place issues the mandatory labelling of fourteen allergenic ingredients whenever used in different food formulations. Among these, six allergenic ingredients, namely milk, egg, peanut, soybean, hazelnut and almond, can be prioritized in light of their higher occurrence in food recalls for undeclared presence with serious risk decision. In this work, we described the results of a comprehensive evaluation of the current literature on MS-based allergen detection aiming at collecting all available information about proteins and peptide markers validated in independent studies for the six allergenic ingredients of interest. The main features of the targeted proteins were commented reviewing all details available about known isoforms and sequence homology particularly in plant-derived allergens. Several critical aspects affecting peptide markers reliability were discussed and according to this evaluation a final short-list of candidate markers was compiled likely to be standardized and implemented in MS methods for allergen analysis.
- Subjects :
- ThRAll
030309 nutrition & dietetics
Proteotypic peptide
[SDV]Life Sciences [q-bio]
Computational biology
Tracing
Biology
Mass spectrometry
medicine.disease_cause
03 medical and health sciences
0404 agricultural biotechnology
Allergen
medicine
peptide marker
Food allergens
incurred foods
Peptide markers
0303 health sciences
Mandatory labelling
Reproducibility of Results
ThRAll Incurred foods
04 agricultural and veterinary sciences
Allergens
040401 food science
Sequence homology
Peptides
Biomarkers
Food Analysis
Food Hypersensitivity
food allergen
Food Science
Subjects
Details
- Language :
- English
- ISSN :
- 09639969
- Database :
- OpenAIRE
- Journal :
- Food Research International, Food Research International, Elsevier, 2020, 128, pp.108747. ⟨10.1016/j.foodres.2019.108747⟩, Food research international (2020). doi:10.1016/j.foodres.2019.108747, info:cnr-pdr/source/autori:Rosa Pilolli1, Chiara Nitride2, Nathalie Gillard3, Anne-Catherine Huet3, Christof van Poucke4, Marc de Loose4, Olivier Tranquet5, Collette Larré5, Karine Adel-Patient6, Hervé Bernard6, E. N. Clare Mills2, and Linda Monaci1*/titolo:CRITICAL REVIEW ON PROTEOTYPIC PEPTIDE MARKERS TRACING FOR SIX ALLERGENIC INGREDIENTS IN INCURRED FOODS BY MASS SPECTROMETRY/doi:10.1016%2Fj.foodres.2019.108747/rivista:Food research international/anno:2020/pagina_da:/pagina_a:/intervallo_pagine:/volume, Pilolli, R, Nitride, C, Gillard, N, Huet, A-C, van Poucke, C, de Loose, M, Tranquet, O, Larré, C, Adel-Patient, K, Bernard, H, Mills, E N C & Monaci, L 2020, ' Critical review on proteotypic peptide marker tracing for six allergenic ingredients in incurred foods by mass spectrometry ', Food Research International, vol. 128, pp. 108747 . https://doi.org/10.1016/j.foodres.2019.108747, Food Research International, 2020, 128, pp.108747. ⟨10.1016/j.foodres.2019.108747⟩
- Accession number :
- edsair.doi.dedup.....6553f3ebede776cc2085914ca56f8048