Antifungal compounds of Xylaria sp., an endophytic fungus isolated from Palicourea marcgravii (Rubiaceae)

Submitted by Guilherme Lemeszenski (guilherme@nead.unesp.br) on 2013-08-22T18:48:35Z No. of bitstreams: 1 S0100-40422005000600011.pdf: 126632 bytes, checksum: 5e2015be95783e04a7a9489829d10c43 (MD5) Made available in DSpace on 2013-08-22T18:48:35Z (GMT). No. of bitstreams: 1 S0100-40422005000600011.pdf: 126632 bytes, checksum: 5e2015be95783e04a7a9489829d10c43 (MD5) Previous issue date: 2005-12-01 Made available in DSpace on 2013-09-30T19:38:33Z (GMT). No. of bitstreams: 2 S0100-40422005000600011.pdf: 126632 bytes, checksum: 5e2015be95783e04a7a9489829d10c43 (MD5) S0100-40422005000600011.pdf.txt: 25236 bytes, checksum: e007c6aec89a03b566b14fec748a8e07 (MD5) Previous issue date: 2005-12-01 Submitted by Vitor Silverio Rodrigues (vitorsrodrigues@reitoria.unesp.br) on 2014-05-20T14:20:55Z No. of bitstreams: 2 S0100-40422005000600011.pdf: 126632 bytes, checksum: 5e2015be95783e04a7a9489829d10c43 (MD5) S0100-40422005000600011.pdf.txt: 25236 bytes, checksum: e007c6aec89a03b566b14fec748a8e07 (MD5) Made available in DSpace on 2014-05-20T14:20:55Z (GMT). No. of bitstreams: 2 S0100-40422005000600011.pdf: 126632 bytes, checksum: 5e2015be95783e04a7a9489829d10c43 (MD5) S0100-40422005000600011.pdf.txt: 25236 bytes, checksum: e007c6aec89a03b566b14fec748a8e07 (MD5) Previous issue date: 2005-12-01 Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) Five compounds, 2-hexyl-3-methyl-butanodioic acid (1), cytochalasin D (2), 7-dechlorogriseofulvin (3), cytochalasin B (4) and griseofulvin (5), have been isolated from the endophytic fungus Xylaria sp., and their structures were elucidated on the basis of spectroscopic data. In the bioautography assay against Cladosporium cladosporioides and Cladosporium sphaerospermum, compounds 1 and 2 were found to be active while compounds 3, 4 and 5 did not show antifungal activity. Universidade Estadual Paulista Instituto de Química Instituto de Botânica Seção de Fisiologia e Bioquímica de Plantas Universidade Federal de Lavras (UFLA) Departamento de Fitopatologia Universidade Estadual Paulista Instituto de Química