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MIRMMR: binary classification of microsatellite instability using methylation and mutations

Authors :
Mingchao Xie
Wen-Wei Liang
Steven M. Foltz
Li Ding
Publication Year :
2017
Publisher :
Oxford University Press, 2017.

Abstract

Summary MIRMMR predicts microsatellite instability status in cancer samples using methylation and mutation information, in contrast to existing methods that rely on observed microsatellites. Additionally, MIRMMR highlights those genetic alterations contributing to microsatellite instability. Availability and implementation Source code is freely available at https://github.com/ding-lab/MIRMMR under the MIT license, implemented in R and supported on Unix/OS X operating systems. Supplementary information Supplementary data are available at Bioinformatics online.

Details

Language :
English
Database :
OpenAIRE
Accession number :
edsair.doi.dedup.....661ff9b13f7e5f0ae204b510f1b53201