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Citric acid bioproduction and downstream processing: Status, opportunities, and challenges
- Source :
- Bioresource technology. 320
- Publication Year :
- 2020
-
Abstract
- Citric acid (CA) has been widely used in different industrial sectors, being produced through fermentation of low-cost feedstock. The development of downstream processes, easier to operate, environmentally friendly, and more economic than precipitation, is certainly a challenge in CA bioproduction. Large volumes of by-products generated in precipitation require treatment before disposal. Adsorption, extraction, and membrane separation have been shown to have a lower environmental impact than precipitation, but the technological maturity of these methods is still limited. However, reactive extraction and adsorption have great potential for industrial applications. This review shows that there is still much to be explored, both about the factors that are intrinsic to the techniques, but also in their combination for new processes' development. This review reports the most recent advances on CA bioproduction, with significant information about recovery and purification methods involving this highly industrially demanded organic acid.
- Subjects :
- 0106 biological sciences
Environmental Engineering
Downstream processing
Renewable Energy, Sustainability and the Environment
Bioengineering
General Medicine
010501 environmental sciences
Raw material
Pulp and paper industry
01 natural sciences
Bioproduction
Environmentally friendly
Citric Acid
chemistry.chemical_compound
Adsorption
Downstream (manufacturing)
chemistry
010608 biotechnology
Fermentation
Environmental science
Citric acid
Waste Management and Disposal
0105 earth and related environmental sciences
Subjects
Details
- ISSN :
- 18732976
- Volume :
- 320
- Database :
- OpenAIRE
- Journal :
- Bioresource technology
- Accession number :
- edsair.doi.dedup.....664e4010844982c59b1db9958fe39871