Back to Search Start Over

Altered gut microbiota composition in immune-impaired Nod2(-/-) mice

Authors :
Joël Doré
Marion Leclerc
Stanislas Mondot
Frédérick Barreau
Ziad Al Nabhani
Karine Le Roux
Patricia Lepage
Jean-Pierre Hugot
Monique Dussaillant
MICrobiologie de l'ALImentation au Service de la Santé (MICALIS)
Institut National de la Recherche Agronomique (INRA)-AgroParisTech
UMR 843 Inflammation intestinale pathologique de l'enfant
Institut National de la Santé et de la Recherche Médicale (INSERM)
Source :
Gut, Gut, BMJ Publishing Group, 2012, 61 (4), pp.634-635. ⟨10.1136/gutjnl-2011-300478⟩
Publication Year :
2011

Abstract

We read with great interest the recently published study by Rehman and colleagues.1 Investigating microbial diversity on faecal and ileal samples from 48 mice using Sanger and 454 techniques, Rehman et al detected increased percentages of Bacteroidetes in the faeces of adult Nod2 −/− mice, whereas Firmicutes levels were significantly higher only in the ileum of Nod2 −/− mice. Since we demonstrated that antibiotic …

Details

ISSN :
14683288 and 00175749
Volume :
61
Issue :
4
Database :
OpenAIRE
Journal :
Gut
Accession number :
edsair.doi.dedup.....671bb7484ae31a309fdd41d9eac95b17
Full Text :
https://doi.org/10.1136/gutjnl-2011-300478⟩