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Bronchiectasis in children after renal or liver transplantation: A report of five cases
- Source :
- Pediatric Transplantation, 8, 71-74. Wiley-Blackwell Publishing Ltd
- Publication Year :
- 2004
- Publisher :
- Wiley, 2004.
-
Abstract
- More effective immunosuppressive treatment in children following organ transplantation has significantly improved the survival of the grafts. Therefore, quality of life, long-term prognosis and adverse drug reactions have become more important. One of the main complications of immunosuppressive drugs is infections of the respiratory tract, but irreversible damage to the airways has not been described after renal or liver transplantation. Five children following transplantation of kidney or liver were referred to the Paediatric Pulmonology department because of chronic respiratory complaints. Pulmonary function tests and HRCT scan were performed as routine patient care. Four children with a renal transplant and one with a liver transplant showed chronic bronchitis and moderate to severe airways obstruction. HRCT showed bronchiectasis in all of them. We speculate that the immunosuppressive treatment (in) directly contributes to irreversible airway damage. We recommend including follow-up of lung function in the post-transplantation protocol and considering bronchiectasis in case of respiratory symptoms, to try preventing further damage to the lung.
- Subjects :
- Male
medicine.medical_specialty
Chronic bronchitis
Adolescent
medicine.medical_treatment
Liver transplantation
Organ transplantation
Internal medicine
Humans
Medicine
Child
Kidney transplantation
Transplantation
Bronchiectasis
business.industry
Respiratory disease
Immunosuppression
respiratory system
medicine.disease
Kidney Transplantation
Liver Transplantation
Respiratory Function Tests
respiratory tract diseases
Surgery
Pediatrics, Perinatology and Child Health
Female
business
Immunosuppressive Agents
Subjects
Details
- ISSN :
- 13993046 and 13973142
- Volume :
- 8
- Database :
- OpenAIRE
- Journal :
- Pediatric Transplantation
- Accession number :
- edsair.doi.dedup.....6748b102f8fc0aa1b45a883cb4573960