Case Studies Illustrating Focal Alzheimer’s, Fluent Aphasia, Late-Onset Memory Loss, and Rapid Dementia

Many dementia subtypes have more shared signs and symptoms than defining ones. We shall review eight cases with four overlapping syndromes and demonstrate how to distinguish the cases. These include focal cortical presentations of Alzheimer’s Disease(AD) (Posterior Cortical Atrophy and Corticobasal Syndrome), fluent aphasia (Semantic Dementia and Logopenic Aphasia), late-onset slowly progressive dementia (Hippocampal Sclerosis and Limbic Predominant AD) and rapidly progressive dementia (Creutzfeldt-Jakob Disease and Limbic Encephalitis). Recognizing the different syndromes described in this paper can help the clinician improve their diagnostic skills leading to improved patient outcomes by early and accurate diagnosis, prompt treatment, appropriate counseling and guidance.