Mechanistic roles of the neighbouring cysteine in enhancing nucleophilicity of catalytic residue in a two‐cysteine succinic semialdehyde dehydrogenase

Authors :: Tanakan Paladkong
Panu Pimviriyakul
Jittima Phonbuppha
Somchart Maenpuen
Pimchai Chaiyen
Ruchanok Tinikul
Source :: The FEBS Journal. 290:2449-2462
Publication Year :: 2022
Publisher :: Wiley, 2022.
Abstract: Succinic semialdehyde dehydrogenase (SSADH) catalyses the conversion of succinic semialdehyde into succinic acid and two electrons are transferred to NAD(P)

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