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Effect of changes in perfusion defect size during serial stress myocardial perfusion imaging on cardiovascular outcomes in patients treated with primary percutaneous coronary intervention after myocardial infarction
- Source :
- Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology. 29(5)
- Publication Year :
- 2021
-
Abstract
- Background. We evaluated the prognostic value of changes in perfusion defect size (PDS) on serial MPS in patients treated with primary percutaneous coronary intervention (PCI) after acute myocardial infarction (AMI). Methods. We enrolled 112 patients treated with primary PCI after AMI who underwent two stress MPS within 1 month and after 6 months. Improvement in PDS was defined as a reduction ‡5%. Remodeling was defined as an increase in left ventricular (LV) end-diastolic volume index ‡20%. Cardiac events included cardiac death, nonfatal MI, unstable angina, repeated revascularization, and heart failure. Results. During a median follow-up of 86 months, 22 events occurred. Event rate was higher (P < .01) in patients with worsening of PDS compared to those with unchanged or improved PDS. Moreover, patients with remodeling had a higher (P < .001) event rate compared to those without. At Cox analysis, worsening of PDS and remodeling resulted independent predictors of events (both P < .01). Patients with both worsening of PDS and remodeling had the worst event-free survival (P
- Subjects :
- medicine.medical_specialty
medicine.medical_treatment
Myocardial Infarction
Revascularization
Myocardial perfusion imaging
Percutaneous Coronary Intervention
Internal medicine
medicine
Humans
Radiology, Nuclear Medicine and imaging
cardiovascular diseases
Myocardial infarction
medicine.diagnostic_test
business.industry
Unstable angina
Myocardial Perfusion Imaging
food and beverages
Percutaneous coronary intervention
Heart
medicine.disease
Perfusion
Heart failure
Conventional PCI
Cardiology
Cardiology and Cardiovascular Medicine
business
Subjects
Details
- ISSN :
- 15326551
- Volume :
- 29
- Issue :
- 5
- Database :
- OpenAIRE
- Journal :
- Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology
- Accession number :
- edsair.doi.dedup.....67c57303bc54b0dffcd27d829e7286cd