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Characterization of synergistic antibacterial effect of silver nanoparticles and ebselen
- Source :
- Artificial cells, nanomedicine, and biotechnology. 47(1)
- Publication Year :
- 2019
-
Abstract
- The emerging and spreading of multi-drug resistant (MDR) bacteria have been becoming one of the most severe threats to human health. Enhancing oxidative stress as mimicking immune system was considered as a potential strategy to fight against infection of MDR bacteria. In this study, we investigated the antibacterial efficiency of such a strategy which combines silver nanoparticles (AgNPs) with ebselen. The results showed that AgNPs and ebselen combination had significant synergistic killing effects both on
- Subjects :
- Azoles
Staphylococcus aureus
Silver
Thioredoxin reductase
Biomedical Engineering
Pharmaceutical Science
Medicine (miscellaneous)
Metal Nanoparticles
02 engineering and technology
Antibacterial effect
Ascorbic Acid
Microbial Sensitivity Tests
Isoindoles
medicine.disease_cause
Silver nanoparticle
03 medical and health sciences
Human health
chemistry.chemical_compound
0302 clinical medicine
Immune system
Organoselenium Compounds
medicine
Escherichia coli
Humans
biology
Chemistry
Ebselen
Drug Synergism
General Medicine
021001 nanoscience & nanotechnology
biology.organism_classification
Drug Resistance, Multiple
Anti-Bacterial Agents
Biochemistry
030220 oncology & carcinogenesis
0210 nano-technology
Reactive Oxygen Species
Bacteria
Oxidative stress
Biotechnology
HeLa Cells
Subjects
Details
- ISSN :
- 2169141X
- Volume :
- 47
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Artificial cells, nanomedicine, and biotechnology
- Accession number :
- edsair.doi.dedup.....67ce9af67f491114793b5b2c26e69ed7