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Normal serum concentrations of anti-Müllerian hormone in women with regular menstrual cycles
- Source :
- Reproductive BioMedicine Online. 21:463-469
- Publication Year :
- 2010
- Publisher :
- Elsevier BV, 2010.
-
Abstract
- Anti-Müllerian hormone (AMH) has become the 'molecule of the moment' in the field of reproductive endocrinology. Indeed, it is valuable as a means of increasing understanding of ovarian pathophysiology and for guiding clinical management across a broad range of conditions. However, no normative values have been established for circulating AMH in healthy women. In this cross-sectional study, 277 healthy females (aged 18-50 years) were included. AMH was measured by commercial enzyme-linked immunosorbent assay. Serum AMH concentrations show a progressive decline with female ageing. The age-related changes in AMH were best fitted by a polynomial function. Mean AMH concentrations were not modified by past use of oral contraceptive and were independent of parity of women. Age-specific normative values for circulating AMH concentration were established. AMH concentrations seem to be independent of the reproductive history of the patient.
- Subjects :
- Adult
Anti-Mullerian Hormone
Oral
Aging
endocrine system
medicine.medical_specialty
Adolescent
endocrine system diseases
Cross-sectional study
media_common.quotation_subject
European Continental Ancestry Group
Reproductive Endocrinology
Normal serum
White People
Reference Values
Internal medicine
medicine
Humans
Ovarian reserve
Contraceptives
Cross-Sectional Studies
Female
Menstrual Cycle
Middle Aged
Menstrual cycle
media_common
biology
urogenital system
business.industry
Obstetrics and Gynecology
Anti-Müllerian hormone
female genital diseases and pregnancy complications
Endocrinology
Reproductive Medicine
Ageing
biology.protein
business
hormones, hormone substitutes, and hormone antagonists
Contraceptives, Oral
Developmental Biology
Hormone
Subjects
Details
- ISSN :
- 14726483
- Volume :
- 21
- Database :
- OpenAIRE
- Journal :
- Reproductive BioMedicine Online
- Accession number :
- edsair.doi.dedup.....67e2dcfcd1b3898802000f9543eaa923