Vascular flow density in pathological myopia: an optical coherence tomography angiography study

Objectives To investigate vascular flow density in pathological myopia with optical coherence tomography (OCT) angiography. Design A prospective comparative study was conducted from December 2015 to March 2016. Setting Participants were recruited in Beijing Tongren Hospital. Participants A total of 131 eyes were enrolled, which were divided into three groups: 45 eyes with emmetropia (EM; mean spherical equivalent (MSE) 0.50D to −0.50D), 41 eyes with high myopia (HM; MSE ≤−6.00D, without pathological changes), and 45 eyes with pathological myopia (PM; MSE ≤−6.00D and axial length (AL) ≥26.5 mm, and with pathological changes). Main outcome measures Macular, choriocapillaris and radial peripapillary capillary (RPC) flow densities were measured and compared between groups, and their relationships with AL and best corrected visual acuity (BCVA) were analysed. Results Significant differences were found in macular, choriocapillaris and RPC flow densities among the three groups (p