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Outcomes of Early Coronary Angiography or Revascularization After Cardiac Surgery

Authors :
Douglas R. Johnston
M.Z. Tong
Eric E. Roselli
Kevin Chen
Eugene H. Blackstone
Faisal G. Bakaeen
A. Marc Gillinov
Shehab AlAnsari
Samir R. Kapadia
Gösta B. Pettersson
Beni R Verma
Edward G. Soltesz
Per Wierup
Lars G. Svensson
Stephen G. Ellis
Conrad Simpfendorfer
Vikram Sharma
Source :
The Annals of thoracic surgery. 111(5)
Publication Year :
2020

Abstract

Background Early coronary ischemic events are uncommon after cardiac surgery, with little known about their management or associated outcomes. We evaluated clinical outcomes of patients undergoing coronary angiography ± percutaneous coronary intervention or redo coronary artery bypass grafting for suspected coronary ischemia within 3 weeks after index cardiac surgery. Methods This is a retrospective observational study based on data from 53,287 patients who underwent cardiac surgery at our institution (1996-2017); 180 patients (0.34%) satisfied the inclusion criteria. The primary outcome was 1-year all-cause mortality. Statistical evaluation involved χ2, analysis of variance, Kaplan-Meier, and receiver operating characteristic curve analyses. Results Most coronary angiography ± percutaneous coronary intervention and redo coronary artery bypass grafting procedures occurred in the first 2 weeks after index cardiac surgery. Patients presenting with ST elevation myocardial infarction (STEMI)/non-STEMI had the lowest 1-year mortality (13.5%), followed by patients with ventricular tachycardia/fibrillation (28.1%), and patients with non–ventricular tachycardia/fibrillation arrest or hemodynamic instability alone the worst (38.6%) (χ2 = 17.3, P = .001). Peak troponin T level after cardiac surgery was strongly predictive of 1-year mortality (area under the curve, 0.74; 95% confidence interval, 0.65-0.84; P Conclusions Although suspected myocardial ischemia requiring coronary angiography or intervention early after cardiac surgery was rare, mortality was high, particularly in presentations other than STEMI/non-STEMI. In patients with overt signs and symptoms of myocardial ischemia after index cardiac surgery, troponin T was not a reliable marker of underlying coronary or graft obstruction but was a robust predictor of 1-year mortality.

Details

ISSN :
15526259
Volume :
111
Issue :
5
Database :
OpenAIRE
Journal :
The Annals of thoracic surgery
Accession number :
edsair.doi.dedup.....67f739f6910325b1a45b785e5ae539dc