Exon 2‐mediated deletion of Trem2 does not worsen metabolic function in diet‐induced obese mice

Authors :: Nathan C. Winn
Elysa M. Wolf
Jamie N. Garcia
Alyssa H. Hasty
Source :: The Journal of Physiology. 600:4485-4501
Publication Year :: 2022
Publisher :: Wiley, 2022.
Abstract: Triggering receptor expressed on myeloid cells 2 (Trem2) is highly expressed on myeloid cells and is involved in cellular lipid homeostasis and inflammatory processes. Trem2 deletion in mice (Trem2

Subjects :: Male
Membrane Glycoproteins
Physiology
Fatty Acids
Mice, Obese
Exons
Diet, High-Fat
Lipids
Mice, Inbred C57BL
Mice
Glucose
Adipose Tissue
Animals
Insulin
Female
Obesity
Insulin Resistance
Receptors, Immunologic
Triglycerides

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