Back to Search
Start Over
Stereotyped distribution of proliferating keratinocytes in disorders affecting the epidermis
- Source :
- The American Journal of dermatopathology. 11(3)
- Publication Year :
- 1989
-
Abstract
- We used the technique of autoradiography after incorporation of tritiated thymidine (/sup 3/H-TdR) to evaluate keratinocyte proliferation in basal, epibasal, and other epidermal layers in 30 diseases affecting the epidermis. The number and proportion of /sup 3/H-TdR-labeled keratinocytes were counted in the different layers of the epidermis. Significant correlations were found between the proliferative indices of the different epidermal layers. Such links indicate that the epidermis responds in a rather stereotyped way to various pathological conditions. There exists some regulation in the distribution, number, and proportion of /sup 3/H-TdR-labeled keratinocytes in the various layers of the epidermis.
- Subjects :
- Statistics as Topic
Dermatology
Biology
Tritium
Skin Diseases
Pathology and Forensic Medicine
Basal (phylogenetics)
chemistry.chemical_compound
Reference Values
Keratin
medicine
Humans
chemistry.chemical_classification
Epidermis (botany)
Cell growth
Scleroprotein
General Medicine
Epithelium
Cell biology
medicine.anatomical_structure
chemistry
Biochemistry
Epidermal Cells
Keratins
Keratinocyte
Thymidine
Subjects
Details
- ISSN :
- 01931091
- Volume :
- 11
- Issue :
- 3
- Database :
- OpenAIRE
- Journal :
- The American Journal of dermatopathology
- Accession number :
- edsair.doi.dedup.....683d654c2a449dd6e864654be0edb89a