Imprint cytologic features of pulmonary large cell neuroendocrine carcinoma: Comparison with classic large cell carcinoma

Authors :: Fumio Horiuchi
Kenzo Hiroshima
Masayuki Baba
Hiroko Saitoh
Hidemi Ohwada
Toshihiko Iizasa
Akira Iyoda
Kiyoshi Shibuya
Yasumitsu Moriya
Takehiko Fujisawa
Source :: Oncology Reports.
Publication Year :: 2004
Publisher :: Spandidos Publications, 2004.
Abstract: The World Health Organization (WHO) categorized large cell neuroendocrine carcinoma (LCNEC) as a variant of large cell carcinoma in 1999. However, cytologic features of these tumors have not yet been adequately characterized. The cytologic features of 24 cases of LCNEC were analyzed and compared to the features of 16 cases of classic large cell carcinoma (CLCC). Giant cells, neutrophils and cytophagocytosis were observed more frequently in CLCC than in LCNEC (p

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