A Highly Sensitive and Specific FDCD Method for Chirality Analysis of Naturally Occurring Pteridines

Authors :: Ning Chen
Hiroshi Ichinose
Kazuhisa Ikemoto
Takashi Sugimoto
Toshiharu Nagatsu
Shizuaki Murata
Source :: Scopus-Elsevier
Publication Year :: 2002
Publisher :: The Japan Institute of Heterocyclic Chemistry, 2002.
Abstract: Absolute configurations of 6-(1-hydroxyalkyl)pterin derivatives are determined by fluorescence detected circular dichroism (FDCD) spectroscopy. This method is at least 10 times more sensitive than CD analysis and specificeven existence of 10 times excess amounts of chiral sugars or nucleic acids.

Subjects :: Pharmacology
Circular dichroism
Stereochemistry
Organic Chemistry
Absolute configuration
Photochemistry
Fluorescence
Analytical Chemistry
Highly sensitive
chemistry.chemical_compound
chemistry
Nucleic acid
Pterin
Chirality (chemistry)
Spectroscopy

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