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Generation and structure-activity relationships of novel imidazo-thienopyridine based TLR7 agonists: application as payloads for immunostimulatory antibody drug-conjugates

Authors :
Michael G. Brant
Graham A.E. Garnett
Joy Guedia
Manuel Lasalle
Samuel Lawn
Mark E. Petersen
Renee Duan
Jose Mendez-Campos
Truman Hirkala-Schaefer
Geoffrey C. Winters
Stuart D. Barnscher
Source :
Bioorganic & Medicinal Chemistry Letters. :129348
Publication Year :
2023
Publisher :
Elsevier BV, 2023.

Details

ISSN :
0960894X
Database :
OpenAIRE
Journal :
Bioorganic & Medicinal Chemistry Letters
Accession number :
edsair.doi.dedup.....68eaaf8136ba0037d3802506c42a7a50
Full Text :
https://doi.org/10.1016/j.bmcl.2023.129348