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Clinical Characteristics and Prognostic Factors in Ankylosing Spondylitis Associated Uveitis
- Source :
- Ocular Immunology and Inflammation. 27:64-69
- Publication Year :
- 2017
- Publisher :
- Informa UK Limited, 2017.
-
Abstract
- To identify the clinical features and prognostic factors of uveitis associated with ankylosing spondylitis (AS).This retrospective, interventional case series study reviewed the medical records of 91 AS patients with uveitis.The characteristics of AS-associated uveitis included male preponderance (70%), average onset in the fourth decade, unilateral manifestation (87.9%), and vitreous involvement or retinal vascular leakage (36.3%). All patients had acute anterior uveitis. The best corrected visual acuity in logMAR improved from 0.8 ± 0.3 to 0.1 ± 0.2. The use of biologic agents was the only significant factor in the multivariate analysis. Patients with vitreous involvement/retinal vascular leakage were more likely to use systemic/peribulbar steroids for inflammation control, and achieved equally favorable visual outcome as in those without vitreous involvement/retinal vascular leakage.The clinical characteristics and profile of visual prognostic factors suggest an association between the severity of ocular inflammation and systemic disease.
- Subjects :
- Adult
Male
Mydriatics
medicine.medical_specialty
Adolescent
Vision Disorders
Visual Acuity
Young Adult
03 medical and health sciences
0302 clinical medicine
medicine
Humans
Immunology and Allergy
Spondylitis, Ankylosing
Fluorescein Angiography
Glucocorticoids
Retrospective Studies
Retinal Vasculitis
030203 arthritis & rheumatology
Ankylosing spondylitis
business.industry
Middle Aged
Prognosis
medicine.disease
Uveitis, Anterior
Dermatology
humanities
body regions
Ophthalmology
Acute Disease
030221 ophthalmology & optometry
Female
Anterior uveitis
business
Uveitis
Case series
Subjects
Details
- ISSN :
- 17445078 and 09273948
- Volume :
- 27
- Database :
- OpenAIRE
- Journal :
- Ocular Immunology and Inflammation
- Accession number :
- edsair.doi.dedup.....692f4969e1380071ba42d8e91ac502ea