3.5 EFFECTS OF BETA-BLOCKERS WITH OR WITHOUT VASODILATING PROPERTIES ON CENTRAL BLOOD PRESSURE: A META-ANALYSIS OF RANDOMIZED TRIALS IN HYPERTENSION

(0.16 1.9 vs -0.12 2.2 m/s; PZ0.4), or any other haemodynamic variable relative to control at six or 12 months (all P > 0.05). Conclusions: Despite many observational studies to suggest that vitamin D supplementation could be a useful therapy for improving aortic stiffness and associated haemodynamic indices, 12-months intervention yielded no improvement in older people with vitamin D deficiency. These results do not support use of vitamin D supplementation to improve cardiovascular health in this patient population.