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Inflammatory markers and bone mass in children with overweight/obesity: the role of muscular fitness
- Source :
- Repositori Universitat Jaume I, Universitat Jaume I
- Publication Year :
- 2019
-
Abstract
- Objectives To examine which inflammatory markers are associated with bone mass and whether this association varies according to muscular fitness in children with overweight/obesity. Methods Plasma interleukin-1β (IL-1β), IL-6, tumor necrosis factor-α (TNF-α), epidermal growth factor, vascular endothelial growth factor A (VEGF), and C-reactive protein were analyzed in 55 children aged 8–11 years. A muscular fitness score was computed. Bone mineral content (BMC) of the total body-less head (TBLH) and lumbar spine (LS) were assessed using dual-energy x-ray absorptiometry. Results IL-6 (β = −0.136) and VEGF (β = −0.099) were associated with TBLH BMC, while TNF-α (β = −0.345) and IL-1β (β = 0.212) were associated with LS BMC (P
- Subjects :
- musculoskeletal diseases
Male
medicine.medical_specialty
Pediatric Obesity
Bone density
Cross-sectional study
Physical fitness
Overweight
03 medical and health sciences
0302 clinical medicine
Absorptiometry, Photon
Bone Density
030225 pediatrics
Internal medicine
growth factors
medicine
Humans
bone health
Child
Muscle, Skeletal
business.industry
Overweight obesity
Age Factors
medicine.disease
Obesity
cytokines
Vascular endothelial growth factor A
Endocrinology
Cross-Sectional Studies
Physical Fitness
Pediatrics, Perinatology and Child Health
Exercise Test
Female
medicine.symptom
Inflammation Mediators
strength
business
childhood obesity
030217 neurology & neurosurgery
Biomarkers
Bone mass
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Journal :
- Repositori Universitat Jaume I, Universitat Jaume I
- Accession number :
- edsair.doi.dedup.....698cd9b0d20c5c1bc30a138a4f9d5039