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Application of marine natural products in drug research
- Source :
- Bioorganicmedicinal chemistry. 35
- Publication Year :
- 2020
-
Abstract
- New diseases are emerging as the environment changes, so drug manufacturers are always on the lookout for new resources to develop effective and safe drugs. In recent years, many bioactive substances have been produced in the marine environment, which represents an alternative resource for new drugs used to combat major diseases such as cancer or inflammation. Many marine-derived medicinal substances are in preclinical or early stage of clinical development, and some marine drugs have been put on the market, such as ET743 (Yondelis®). This review presents the sources, activities, mechanisms of action and syntheses of bioactive substances based on marine natural products in clinical trials and on the market, which is helpful to understand the progress of drug research by application of marine natural products.
- Subjects :
- Drug
Biological Products
Resource (biology)
Molecular Structure
Chemistry
media_common.quotation_subject
Organic Chemistry
Clinical Biochemistry
Pharmaceutical Science
Biochemistry
Natural (archaeology)
Risk analysis (engineering)
Drug Discovery
Molecular Medicine
Molecular Biology
media_common
Subjects
Details
- ISSN :
- 14643391
- Volume :
- 35
- Database :
- OpenAIRE
- Journal :
- Bioorganicmedicinal chemistry
- Accession number :
- edsair.doi.dedup.....69d56bc8e36e0d3e2a4096a78774ae47