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A novel strategy for forensic age prediction by DNA methylation and support vector regression model

Authors :
Yaran Yang
Bingbing Xie
Jiangwei Yan
Hongzhu Qu
Guangyu Wang
Yi Shi
Lan Hu
Lei Feng
Cheng Xu
Xiangdong Fang
Zhao Zhao
Source :
Scientific Reports
Publication Year :
2015
Publisher :
Nature Publishing Group, 2015.

Abstract

High deviations resulting from prediction model, gender and population difference have limited age estimation application of DNA methylation markers. Here we identified 2,957 novel age-associated DNA methylation sites (P 2 > 0.5) in blood of eight pairs of Chinese Han female monozygotic twins. Among them, nine novel sites (false discovery rate

Details

Language :
English
ISSN :
20452322
Database :
OpenAIRE
Journal :
Scientific Reports
Accession number :
edsair.doi.dedup.....69ee621f579229ff9d39e44d188fb7a7
Full Text :
https://doi.org/10.1038/srep17788