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A novel strategy for forensic age prediction by DNA methylation and support vector regression model
- Source :
- Scientific Reports
- Publication Year :
- 2015
- Publisher :
- Nature Publishing Group, 2015.
-
Abstract
- High deviations resulting from prediction model, gender and population difference have limited age estimation application of DNA methylation markers. Here we identified 2,957 novel age-associated DNA methylation sites (P 2 > 0.5) in blood of eight pairs of Chinese Han female monozygotic twins. Among them, nine novel sites (false discovery rate
- Subjects :
- Adult
Forensic Genetics
Genetic Markers
Male
False discovery rate
China
Multivariate statistics
Support Vector Machine
Population
Biology
Polymerase Chain Reaction
Article
Bayesian multivariate linear regression
Statistics
Linear regression
Humans
education
Aged
Aged, 80 and over
Genetics
education.field_of_study
Multidisciplinary
Regression analysis
DNA Methylation
Middle Aged
Support vector machine
Regression Analysis
CpG Islands
Female
Nonlinear regression
Subjects
Details
- Language :
- English
- ISSN :
- 20452322
- Database :
- OpenAIRE
- Journal :
- Scientific Reports
- Accession number :
- edsair.doi.dedup.....69ee621f579229ff9d39e44d188fb7a7
- Full Text :
- https://doi.org/10.1038/srep17788