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Low-risk polycythemia vera treated with phlebotomies: clinical characteristics, hematologic control and complications in 453 patients from the Spanish Registry of Polycythemia Vera

Authors :
Triguero, Ana
Pedraza, Alexandra
Pérez-Encinas, Manuel
Mata-Vázquez, María Isabel
Vélez, Patricia
Fox, Laura
Gómez-Calafat, Montse
García-Delgado, Regina
Gasior, Mercedes
Ferrer-Marín, Francisca
García-Gutiérrez, Valentín
Angona, Anna
Gómez-Casares, María Teresa
Cuevas, Beatriz
Martínez, Clara
Pérez, Raúl
Raya, José María
Guerrero, Lucía
Murillo, Ilda
Bellosillo, Beatriz
Hernández-Boluda, Juan Carlos
Sanz, Cristina
Álvarez-Larrán, Alberto
On behalf of the MPN Spanish Group (GEMFIN)
Institut Català de la Salut
[Triguero A, Pedraza A] Hospital Clinic de Barcelona, Barcelona, Spain. [Pérez-Encinas M] Complejo Hospitalario Universitario de Santiago, Santiago de Compostela, Spain. [Mata-Vázquez MI] Hospital Costa del Sol, Marbella, Spain. [Vélez P] Hospital del Mar, Barcelona, Spain. [Fox L] Vall d’Hebron Hospital Universitari, Barcelona, Spain. Experimental Hematology Group, Vall d’Hebron Institute of Oncology (VHIO), Barcelona, Spain
Vall d'Hebron Barcelona Hospital Campus
Source :
ANNALS OF HEMATOLOGY, r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau, instname, Ann Hematol, r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA, Scientia
Publication Year :
2022
Publisher :
SPRINGER, 2022.

Abstract

Myelofibrosis; Phlebotomies; Thrombosis Mielofibrosi; Flebotomies; Trombosi Mielofibrosis; Flebotomías; Trombosis Hematological control, incidence of complications, and need for cytoreduction were studied in 453 patients with low-risk polycythemia vera (PV) treated with phlebotomies alone. Median hematocrit value decreased from 54% at diagnosis to 45% at 12 months, and adequate hematocrit control over time ( 60 years, and microvascular symptoms constituted the main indications for starting cytoreduction. Median duration without initiating cytoreduction was significantly longer in patients younger than 50 years (

Details

ISSN :
09395555
Database :
OpenAIRE
Journal :
ANNALS OF HEMATOLOGY, r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau, instname, Ann Hematol, r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA, Scientia
Accession number :
edsair.doi.dedup.....6a57fe3c99c8b1262eaefaa9c8b89b86