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Assessment of vaccine effectiveness during measles outbreak in the Federation of Bosnia and Herzegovina, 2014-2015
- Source :
- Central European Journal of Public Health. 26:79-82
- Publication Year :
- 2018
- Publisher :
- National Institute of Public Health, 2018.
-
Abstract
- Objective: Between February 2014 and September 2015 a large measles outbreak (5,084 cases) occurred in the Federation of Bosnia and Herzegovina (FB&H). The aim of this study is to assess the effectiveness of routine measles vaccination in the FB&H. Methods: We conducted an analysis of the resurgence period surveillance data and a retrospective cohort study involving primary school aged children in randomly selected schools. Results: Measles cases occurred among all age groups, mostly among the unvaccinated. Among fully immunized, 2.1% contracted measles. Measles vaccine effectiveness was high. The study indicates that one dose reduced the risk for measles by 91.9% (95% CI: 81.4-96.4%), two doses reduced the risk by 97.3% (95% CI: 95.5-98.4%). No evidence of waning immunity was found. Our survey reveals that a significant number of children had no immunization status registered. Conclusions: The results of this study suggest that the resurgence was likely caused by an accumulation of measles-susceptible children not being vaccinated. This vaccine effectiveness study does not support possible vaccination failure as a contributing factor.
- Subjects :
- Male
0301 basic medicine
Pediatrics
medicine.medical_specialty
Adolescent
Measles Vaccine
030106 microbiology
Measles outbreak
Measles
Disease Outbreaks
03 medical and health sciences
Vaccination failure
0302 clinical medicine
Humans
Medicine
030212 general & internal medicine
Child
Immunization Schedule
Retrospective Studies
Bosnia and Herzegovina
business.industry
Public Health, Environmental and Occupational Health
Outbreak
Retrospective cohort study
General Medicine
medicine.disease
Vaccination
Immunization
Child, Preschool
Female
Measles vaccine
business
Subjects
Details
- ISSN :
- 18031048 and 12107778
- Volume :
- 26
- Database :
- OpenAIRE
- Journal :
- Central European Journal of Public Health
- Accession number :
- edsair.doi.dedup.....6a5bc1914e0bc539096e4469c880de65
- Full Text :
- https://doi.org/10.21101/cejph.a4754