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Predictors of New-Onset Atrial Tachyarrhythmias After Transcatheter Atrial Septal Defect Closure in Adults
- Source :
- Heart, lungcirculation. 30(9)
- Publication Year :
- 2020
-
Abstract
- New-onset atrial tachyarrhythmia (ATA) often develops after atrial septal defect (ASD) closure. Its development raises some potential concerns such as stroke and bleeding complications caused by anticoagulant therapy and limited access to the left atrium for catheter ablation. Although it is essential to identify the risk factors of new-onset ATA, few studies have examined these factors. This study investigated unknown risk factors for the development of new-onset ATA after transcatheter ASD closure in patients without a history of ATA.A total of 238 patients without a history of ATA, aged ≥18 years and who underwent transcatheter ASD closure at the current hospital were reviewed. Patient characteristics were compared between the groups with and without new-onset ATA. The factors associated with new-onset ATA were examined using univariate and multivariable analyses.Thirteen (13) (5.5%) patients experienced ATA during follow-up (mean, 21±14 months). Compared with patients without new-onset ATA, patients with new-onset ATA were older (48±18 vs 66±11 years; p0.001) and had high brain natriuretic peptide (BNP) levels (36±36 vs 177±306 pg/mL; p0.001). On multivariable analysis, BNP ≥40 pg/mL before ASD closure was associated with new-onset ATA after adjusting for age (OR, 4.91; 95% CI, 1.22-19.8; p=0.025).Patients with BNP levels40 pg/mL before transcatheter ASD closure may have a higher risk of developing new-onset ATA.
- Subjects :
- Pulmonary and Respiratory Medicine
Adult
medicine.medical_specialty
Cardiac Catheterization
Adolescent
medicine.medical_treatment
Left atrium
Patient characteristics
Catheter ablation
030204 cardiovascular system & hematology
Heart Septal Defects, Atrial
New onset
03 medical and health sciences
0302 clinical medicine
Internal medicine
Tachycardia
medicine
Humans
In patient
030212 general & internal medicine
Heart Atria
Stroke
business.industry
Atrial septal defect closure
medicine.disease
Brain natriuretic peptide
medicine.anatomical_structure
Treatment Outcome
Cardiology
Cardiology and Cardiovascular Medicine
business
Subjects
Details
- ISSN :
- 14442892
- Volume :
- 30
- Issue :
- 9
- Database :
- OpenAIRE
- Journal :
- Heart, lungcirculation
- Accession number :
- edsair.doi.dedup.....6ab416cd74e6967375e5922c3e567033