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Management of uncommon chemotherapy-induced emergencies

Management of uncommon chemotherapy-induced emergencies

Authors :
Carys Morgan
Jeremy P Braybrooke
Tania Tillett
Thankamma Ajithkumar
Source :
The Lancet Oncology. 12:806-814
Publication Year :
2011
Publisher :
Elsevier BV, 2011.

Abstract

Chemotherapy can induce various clinical emergencies. Prompt recognition and management of these adverse events are important for avoiding further morbidity and mortality. Some events such as hypersensitivity and extravasation are quite common, whereas emergencies such as neutropenic typhlitis, pancreatitis, and acute haemolysis are very rare. Little information exists on the management of rare chemotherapy-induced emergencies that affect fewer than 1% of patients. We review these uncommon chemotherapy-induced life-threatening emergencies, their pathogenesis and management, and recommendations for rechallenge with the offending chemotherapy.

Details

ISSN :
14702045
Volume :
12
Database :
OpenAIRE
Journal :
The Lancet Oncology
Accession number :
edsair.doi.dedup.....6abfbd33eae65aba6d44b35440b07238
Full Text :
https://doi.org/10.1016/s1470-2045(10)70208-4