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Experimental evaluation of the 'gastric barrier' in CSF shunt infections
- Source :
- The Journal of surgical research. 16(5)
- Publication Year :
- 1974
-
Abstract
- The historical background, rational and experimental evidence for the presence and function of a “gastric barrier” has been reviewed. In vitro and in vivo experiments were carried out to determine the effect of pH on common CSF shunt infecting organisms. A critical pH level of 3.5–3.8 has been established for a successful kill rate after 15 min of exposure, documenting the barrier theory to be a function of pH and time of exposure. The use of low pH supplement feedings (Coca Cola and ginger ale) is feasible and may be desirable. Some possible disadvantages when employed clinically are enumerated.
- Subjects :
- Pathology
medicine.medical_specialty
Serratia
Time Factors
Kill rate
Staphylococcus
Pharmacology
Beverages
Eating
Feces
In vivo
medicine
Animals
Humans
Child
Ph level
Gastric Juice
Csf shunt
business.industry
Infant
Bacterial Infections
Fasting
Gastric Acidity Determination
Haplorhini
Hydrogen-Ion Concentration
Coca cola
In vitro
Cerebrospinal Fluid Shunts
Milk
Child, Preschool
Pseudomonas aeruginosa
Macaca
Surgery
Infant Food
business
Sleep
Subjects
Details
- ISSN :
- 00224804
- Volume :
- 16
- Issue :
- 5
- Database :
- OpenAIRE
- Journal :
- The Journal of surgical research
- Accession number :
- edsair.doi.dedup.....6adaf26b17ece3293ac5a0bad9aaf1a8