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Nonmetastatic castration‐resistant prostate cancer treated with salvage focal brachytherapy after external beam radiotherapy
- Source :
- IJU Case Reports, IJU Case Reports, Vol 4, Iss 4, Pp 228-230 (2021)
- Publication Year :
- 2021
- Publisher :
- John Wiley and Sons Inc., 2021.
-
Abstract
- Introduction The efficacy of salvage local therapy after external beam radiotherapy has recently gained attention. However, a challenge with these therapies is the risk of significant genitourinary and gastrointestinal toxicity. Focal brachytherapy may be a treatment option because of its potential to reduce side effects. Case presentation A patient with castration-resistant prostate cancer was found to be free of metastases on whole-body magnetic resonance imaging following external beam radiotherapy, and prostate biopsy revealed a localized recurrence in the ventral prostate. The patient underwent salvage focal brachytherapy and had a prostate-specific antigen progression-free survival of 23 months. No adverse effects were observed following salvage brachytherapy. Conclusion Our case suggests that salvage focal brachytherapy may be an effective local treatment option for nonmetastatic castration-resistant prostate cancer that has relapsed after external beam radiotherapy, wherein the lesion is confined to a small area within the prostate.
- Subjects :
- medicine.medical_specialty
Prostate biopsy
Urology
medicine.medical_treatment
Brachytherapy
brachytherapy
hemi‐gland focal therapy
Salvage therapy
Case Report
Case Reports
prostatic neoplasms
Prostate cancer
Prostate
Medicine
External beam radiotherapy
salvage therapy
radiotherapy
medicine.diagnostic_test
business.industry
Magnetic resonance imaging
castration‐resistant
medicine.disease
Diseases of the genitourinary system. Urology
Radiation therapy
medicine.anatomical_structure
Radiology
RC870-923
business
Subjects
Details
- Language :
- English
- ISSN :
- 2577171X
- Volume :
- 4
- Issue :
- 4
- Database :
- OpenAIRE
- Journal :
- IJU Case Reports
- Accession number :
- edsair.doi.dedup.....6b1f2c856c473066afc9e6dacfcd73ce