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Supplementary Materials and Methods from ASTX660, a Novel Non-peptidomimetic Antagonist of cIAP1/2 and XIAP, Potently Induces TNFα-Dependent Apoptosis in Cancer Cell Lines and Inhibits Tumor Growth

Authors :
Gianni Chessari
Nicola G. Wallis
Nicola E. Wilsher
Pamela A. Williams
Neil T. Thompson
Tomoko Smyth
Sharna J. Rich
Joanne M. Munck
Vanessa Martins
John F. Lyons
Christopher N. Johnson
Jong Sook Ahn
Edward J. Lewis
George A. Ward
Publication Year :
2023
Publisher :
American Association for Cancer Research (AACR), 2023.

Abstract

Preparation of 2-chloro-1-{6-[(4-fluorophenyl)methyl]-5-(hydroxymethyl)-3,3-dimethyl-1H,2H,3H-pyrrolo[3,2-b]pyridin-1-yl}ethan-1-one

Details

Database :
OpenAIRE
Accession number :
edsair.doi.dedup.....6b2eeafc320764ac1f08c123c93107d2
Full Text :
https://doi.org/10.1158/1535-7163.22505329.v1