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Emerging Technologies to Prevent Pregnancy and Sexually Transmitted Infections in Women
- Source :
- Seminars in reproductive medicine. 34(3)
- Publication Year :
- 2016
-
Abstract
- Worldwide, there continues to be a large unmet need for family planning and sexually transmitted infection (STI) prevention methods. Multipurpose prevention technology (MPT) is a general term encompassing any single prevention methodology targeting more than one STI (including HIV) and/or pregnancy. While innovation has been slow over the past several decades, recent scientific advances have resulted in new products entering clinical trials. This review focuses primarily on multipurpose technologies that are designed to prevent pregnancy and HIV. To examine the current state of MPTs, we outline key discoveries of biologic mechanisms that influence susceptibility of the female genital tract to HIV and STIs, and review the effects of hormonal contraception on HIV susceptibility. We discuss the state of currently available HIV prevention strategies for women, and their interactions with hormonal contraceptive products. Finally, we describe MPTs currently in preclinical and clinical trials and propose ongoing questions requiring research to help advance the field.
- Subjects :
- medicine.medical_specialty
Endocrinology, Diabetes and Metabolism
media_common.quotation_subject
Population
Sexually Transmitted Diseases
Fertility
03 medical and health sciences
0302 clinical medicine
Endocrinology
Acquired immunodeficiency syndrome (AIDS)
Pregnancy
Physiology (medical)
Medicine
Humans
030212 general & internal medicine
Intensive care medicine
education
media_common
Gynecology
education.field_of_study
030505 public health
business.industry
virus diseases
Obstetrics and Gynecology
Pregnancy, Unplanned
medicine.disease
Clinical trial
Clinical research
Contraception
Reproductive Medicine
Family planning
Hormonal contraception
Female
0305 other medical science
business
Subjects
Details
- ISSN :
- 15264564
- Volume :
- 34
- Issue :
- 3
- Database :
- OpenAIRE
- Journal :
- Seminars in reproductive medicine
- Accession number :
- edsair.doi.dedup.....6b3c8c9c07bb33277e1833e8f5a503c1